Structure of PDB 4upl Chain A

Receptor sequence
>4uplA (length=555) Species: 246200 (Ruegeria pomeroyi DSS-3) [Search protein sequence]
TAVMNILFIMFDQLRWDYLSCYGHKTLNTPHIDRLAAKGVRFDRAYIQSP
ICGSSRMSTYTGRYVHSHGASWNGIPLKVGEMTMGDHLRAAGMGCWLVGK
THMRADEEGMARLGLEPDSLIGARVAECGFDVFERDDGMLPEGPDGYYDP
DGAKEYNKFLRAKGYESDNPWHDFANSGLDDEGNVQSGWFLKNATRPANI
AEEDSETPYLTSRAMEFIEQQTGPWCCHLSYIKPHWPYIVPEPYASMFGP
EHVQDVVRSDSERQNAHPLFKAFMDTKVGEAFSRQEVRDAVIPAYMGLIK
QADDQMGRLFKWLEDTGRMQDTMIVLTSDHGDFLGDHWMGEKTFFHDAST
RVPLIIYDPRPEADATRGSVCDALVESIDLAPTFVEAAGGKPAMHILEGE
SLIPILHGARDHTLRDHVICEYDFSASPIAHLNDISVRQAVMFMVADKNW
KLIHFEADPRPMLFDLKNDPQELVDLGGDPAHADVIAGMYDKLFRWTRRQ
SQRTTRSEEQLIAMRTKSRKRGIVLGIYDENETPLELTVKYRDRKARPYK
DYLKG
3D structure
PDB4upl Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
ChainA
Resolution1.805 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D9 Q10 C49 R53 K97 H99 G140 H232 D326 H327 K339
Catalytic site (residue number reindexed from 1) D12 Q13 C52 R56 K100 H102 G143 H235 D329 H330 K342
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D9 C49 D326 H327 D12 C52 D329 H330
Gene Ontology
Molecular Function
GO:0008484 sulfuric ester hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4upl, PDBe:4upl, PDBj:4upl
PDBsum4upl
PubMed30497259
UniProtQ5LMH0

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