Structure of PDB 4upi Chain A

Receptor sequence
>4upiA (length=548) Species: 246200 (Ruegeria pomeroyi DSS-3) [Search protein sequence]
NRNILWIMCDQLRFDYLSCYGHERLNTPNIDKLAKRGVRFTNAYVQATVA
GPSRMSAYTGRYVRSHGSTQNGIPLRVGEPTLGDHLRDVGMRNVLIGKTH
MRPDLDGMKRLGIDPDSEIGARVGEGGFDAFDRDDGVHPTGYRKKEPAYN
DYLRHAGFQAENPWEFWANSAEGKGGENQSGWLLTHADKPARVPEEHSET
AYMTRRAMEFMEAAEKDGRPWCAHLSYIKPHWPYIVPAPYHDMFGPDDVK
PAVRSDEELKAAHPLFKAMTEEVYSRNFARDEVREKVIPAYMGLIKQIDD
QLGQLFAFMQERGLDENTMIVFTADHGDYLGDHWMGEKYLFYEAAAKVPL
IIYDPSDKADATRGTVSDALVEMIDLAPTFVDYAGGVPPMHILEGKSLLP
LLHDDDSSWDRQYVFSELDYSNLPARLKLGRDIQDCRATMVFDGRYKLVE
VMGFAPILFDLEVDPDELKDLGRDPSAEEVRQRLTSALDAWHRNTRQRIT
KSDAAYRALDPVLRESDPDLMAGVIIGYWDEDEVEAEKRRIARILGEN
3D structure
PDB4upi Balancing Specificity and Promiscuity in Enzyme Evolution: Multidimensional Activity Transitions in the Alkaline Phosphatase Superfamily.
ChainA
Resolution1.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D13 Q14 A53 R57 K101 H103 H141 H234 D328 H329 K341
Catalytic site (residue number reindexed from 1) D10 Q11 A50 R54 K98 H100 H138 H231 D325 H326 K338
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D13 X53 D328 H329 N551 D10 X50 D325 H326 N548
Gene Ontology
Molecular Function
GO:0008484 sulfuric ester hydrolase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4upi, PDBe:4upi, PDBj:4upi
PDBsum4upi
PubMed30497259
UniProtQ5LLA5

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