Structure of PDB 4up5 Chain A

Receptor sequence
>4up5A (length=85) Species: 9606 (Homo sapiens) [Search protein sequence]
GVYPCGACRSEVNDDQDAILCEASCQKWFHRECTGMTESAYGLLTTEASA
VWACDLCVYVFTTHLANTAAEAVLQGRADSILAYH
3D structure
PDB4up5 Competitive Binding of a Benzimidazole to the Histone-Binding Pocket of the Pygo Phd Finger.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C330 C333 H355 C358 C5 C8 H30 C33
BS02 ZN A C346 C350 C379 C382 C21 C25 C54 C57
BS03 94W A A332 F354 T359 D380 A7 F29 T34 D55 MOAD: Kd=2.5mM
PDBbind-CN: -logKd/Ki=2.60,Kd=2.5mM
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