Structure of PDB 4uj4 Chain A

Receptor sequence
>4uj4A (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
RDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSI
QVDGKTIKAQIWDTAGLERYRAITSAYYRGAVGALLVYDIAKHLTYENVE
RWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNGLSFIET
SALDSTNVEAAFQTILTEIYRIVSQK
3D structure
PDB4uj4 Structure of Rab11-FIP3-Rabin8 reveals simultaneous binding of FIP3 and Rabin8 effectors to Rab11.
ChainA
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A S20 G21 G23 K24 S25 N26 F36 L38 S40 T43 G69 K125 D127 S154 A155 L156 S17 G18 G20 K21 S22 N23 F33 L35 S37 T40 G66 K122 D124 S151 A152 L153
BS02 MG A S25 T43 S22 T40
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4uj4, PDBe:4uj4, PDBj:4uj4
PDBsum4uj4
PubMed26258637
UniProtP62491|RB11A_HUMAN Ras-related protein Rab-11A (Gene Name=RAB11A)

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