Structure of PDB 4uec Chain A

Receptor sequence
>4uecA (length=171) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
PHMKHPLMNVWTLWYLENDRSKSWEDMQNEITSFDTVEDFWSLYNHIKPP
SEIKLGSDYSLFKKNIRPMWEDAANKQGGRWVITLNKSSKTDLDNLWLDV
LLCLIGEAFDHSDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLR
DALRLGRNNSLQYQLHKDTMV
3D structure
PDB4uec Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MGT A W89 M134 W135 E136 R188 K193 W197 W24 M69 W70 E71 R123 K128 W132
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4uec, PDBe:4uec, PDBj:4uec
PDBsum4uec
PubMed25702871
UniProtP48598|IF4E_DROME Eukaryotic translation initiation factor 4E1 (Gene Name=eIF4E1)

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