Structure of PDB 4ucc Chain A

Receptor sequence
>4uccA (length=223) Species: 11259 (Human respiratory syncytial virus A2) [Search protein sequence]
DSIDTPNYDVQKHINKLCGMLLITEDANHKFTGLIGMLYAMSRLGREDTI
KILRDAGYHVKANGVDVTTHRQDINGKEMKFEVLTLASLTTEIQINIEIE
SRKSYKKMLKEMGEVAPEYRHDSPDCGMIILCIAALVITKLAAGDRSGLT
AVIRRANNVLKNEMKRYKGLLPKDIANSFYEVFEKHPHFIDVFVHFGIAQ
SSTRGGSRVEGIFAGLFMNAYGL
3D structure
PDB4ucc A Druggable Pocket at the Nucleocapsid/Phosphoprotein Interaction Site of the Human Respiratory Syncytial Virus.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZKW A M50 E128 S131 R132 Y135 R150 H151 M20 E98 S101 R102 Y105 R120 H121 MOAD: Kd=48uM
PDBbind-CN: -logKd/Ki=4.32,Kd=48uM
Gene Ontology
Cellular Component
GO:0019013 viral nucleocapsid

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Molecular Function

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Cellular Component
External links
PDB RCSB:4ucc, PDBe:4ucc, PDBj:4ucc
PDBsum4ucc
PubMed26246564
UniProtP03418|NCAP_HRSVA Nucleoprotein (Gene Name=N)

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