Structure of PDB 4uc0 Chain A

Receptor sequence
>4uc0A (length=247) Species: 373 (Agrobacterium vitis) [Search protein sequence]
PAVDLLIDRLNGLLPRIAIVLGSGLGGLVDEVENAVRIPFADIPGFPKEL
VAGLFAGQPIIMLAGRVHYYEEGDAAAMRLPIETLASLGVTTLILTNAAG
SLRADMPPGSVMQLIDHINFSGHNPLIGETGDGRFVGMTQAYDGELAEAM
RRAADAEDISLSSGVYMWFSGPSFETPAEIRMARTLGADAVGMSTVPEVI
LARFFGLKVAAASVITNYGAGMTDMAPIGGRRLVAILKRMIVDGGAD
3D structure
PDB4uc0 Crystal Structure Of a purine nucleoside phosphorylase (PSI-NYSGRC-029736) from Agrobacterium vitis
ChainA
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S25 H78 Y80 E81 A108 M203 S204 N227 G229
Catalytic site (residue number reindexed from 1) S23 H68 Y70 E71 A98 M193 S194 N217 G219
Enzyme Commision number 2.4.2.1: purine-nucleoside phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HPA A A109 G110 F184 E185 G202 M203 T226 N227 A99 G100 F174 E175 G192 M193 T216 N217
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009116 nucleoside metabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4uc0, PDBe:4uc0, PDBj:4uc0
PDBsum4uc0
PubMed
UniProtB9JYS2

[Back to BioLiP]