Structure of PDB 4ube Chain A

Receptor sequence
>4ubeA (length=331) Species: 233413 (Mycobacterium tuberculosis variant bovis AF2122/97) [Search protein sequence]
EDLYFQSHMTIAVTGSIATDHLMRFPGRFSEQLLPEHLHKVSLSFLVDDL
VMHRGGVAGNMAFAIGVLGGEVALVGAAGADFADYRDWLKARGVNCDHVL
ISETAHTARFTCTTDVDMAQIASFYPGAMSEARNIKLADVVSAIGKPELV
IIGANDPEAMFLHTEECRKLGLAFAADPSQQLARLSGEEIRRLVNGAAYL
FTNDYEWDLLLSKTGWSEADVMAQIDLRVTTLGPKGVDLVEPDGTTIHVG
VVPETSQTDPTGVGDAFRAGFLTGRSAGLGLERSAQLGSLVAVLVLESTG
TQEWQWDYEAAASRLAGAYGEHAAAEIVAVL
3D structure
PDB4ube High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme
ChainA
Resolution1.933 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.1.20: adenosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2FA A S8 D12 G48 V49 N52 F102 F116 M121 A146 Q172 Q173 G254 D257 S16 D20 G56 V57 N60 F110 F124 M129 A154 Q180 Q181 G262 D265
Gene Ontology
Molecular Function
GO:0004001 adenosine kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0006166 purine ribonucleoside salvage
GO:0016310 phosphorylation
GO:0044209 AMP salvage

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4ube, PDBe:4ube, PDBj:4ube
PDBsum4ube
PubMed
UniProtP83736|ADOK_MYCBO Adenosine kinase (Gene Name=adoK)

[Back to BioLiP]