Structure of PDB 4uaj Chain A

Receptor sequence
>4uajA (length=280) Species: 666 (Vibrio cholerae) [Search protein sequence]
GVKKWECTVISNDNKATFIKELKLAIPDGESVPFRAGGYIQIEAPAHHVK
YADFDVPEKYRGDWDKFNLFRYESKVDEPIIRAYSMANYPEEFGIIMLNV
RIATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFGEFFAKDTDAEMVF
IGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAA
ENDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEYYMC
GPPMMNAAVINMLKNLGVEEENILLDDFGG
3D structure
PDB4uaj Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
ChainA
Resolution2.7019 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.2.1.1: NADH:ubiquinone reductase (Na(+)-transporting).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A R210 A211 Y212 S213 N227 V228 A231 T232 P233 V240 P241 G243 Q244 M245 S246 F406 R82 A83 Y84 S85 N99 V100 A103 T104 P105 V112 P113 G115 Q116 M117 S118 F278
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4uaj, PDBe:4uaj, PDBj:4uaj
PDBsum4uaj
PubMed25471880
UniProtA5F5Y4|NQRF_VIBC3 Na(+)-translocating NADH-quinone reductase subunit F (Gene Name=nqrF)

[Back to BioLiP]