Structure of PDB 4u9u Chain A

Receptor sequence
>4u9uA (length=279) Species: 666 (Vibrio cholerae) [Search protein sequence]
VKKWECTVISNDNKATFIKELKLAIPDGESVPFRAGGYIQIEAPAHHVKY
ADFDVPEKYRGDWDKFNLFRYESKVDEPIIRAYSMANYPEEFGIIMLNVR
IATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFGEFFAKDTDAEMVFI
GGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVEDFDGLAAE
NDNFVWHCALSDPQPEDNWTGYTGFIHNVLYENYLKDHEAPEDCEYYMCG
PPMMNAAVINMLKNLGVEEENILLDDFGG
3D structure
PDB4u9u Structure of the V. cholerae Na+-pumping NADH:quinone oxidoreductase.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.2.1.1: NADH:ubiquinone reductase (Na(+)-transporting).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A Y167 R210 A211 Y212 S213 N227 A231 T232 P233 V240 P241 G243 Q244 M245 S246 F406 Y38 R81 A82 Y83 S84 N98 A102 T103 P104 V111 P112 G114 Q115 M116 S117 F277
BS02 MG A K143 Y188 R315 M317 K14 Y59 R186 M188
BS03 NA A A327 N330 D331 F333 A198 N201 D202 F204
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006814 sodium ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u9u, PDBe:4u9u, PDBj:4u9u
PDBsum4u9u
PubMed25471880
UniProtQ9X4Q8|NQRF_VIBCH Na(+)-translocating NADH-quinone reductase subunit F (Gene Name=nqrF)

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