Structure of PDB 4u89 Chain A

Receptor sequence
>4u89A (length=225) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
VGTLVASVLPATVFEDLAYAELYSDPPGLTPLPEEAPLIARSVAKRRNEF
ITVRHCARIALDQLGVPPAPILKGDKGEPCWPDGMVGSLTHCAGYRGAVV
GRRDAVRSVGIDAEPHDVLPNGVLDAISLPAERADMPRTMPAALHWDRIL
FCAKEATYKAWFPLTKRWLGFEDAHITFETDSTGWTGRFVSRILIDGSTL
SGPPLTTLRGRWSVERGLVLTAIVL
3D structure
PDB4u89 X-ray structure of the 4'-phosphopantetheinyl transferase PptT from Mycobacterium tuberculosis
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.8.7: holo-[acyl-carrier-protein] synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A R48 R56 K75 K78 G79 E80 P81 L91 T92 H93 D114 K156 E157 Y160 K161 F164 W170 L171 G172 F173 R46 R54 K73 K76 G77 E78 P79 L89 T90 H91 D112 K154 E155 Y158 K159 F162 W168 L169 G170 F171
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0005515 protein binding
GO:0008897 holo-[acyl-carrier-protein] synthase activity
GO:0016740 transferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0046872 metal ion binding
Biological Process
GO:0009237 siderophore metabolic process
GO:0009239 enterobactin biosynthetic process
GO:0019290 siderophore biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0009366 enterobactin synthetase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u89, PDBe:4u89, PDBj:4u89
PDBsum4u89
PubMed
UniProtO33336|PPTT_MYCTU 4'-phosphopantetheinyl transferase PptT (Gene Name=pptT)

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