Structure of PDB 4u1s Chain A

Receptor sequence
>4u1sA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQISQRKLEA
ARVAEQLRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWTAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
3D structure
PDB4u1s A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
ChainA
Resolution1.76 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 R62 N63 Q70 T73 S77 Y84 Y99 N114 Y116 S143 V152 L156 Y159 W167 Y171 Y8 R63 N64 Q71 T74 S78 Y85 Y100 N115 Y117 S144 V153 L157 Y160 W168 Y172
External links
PDB RCSB:4u1s, PDBe:4u1s, PDBj:4u1s
PDBsum4u1s
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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