Structure of PDB 4u1n Chain A

Receptor sequence
>4u1nA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSHSMRYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEA
ARVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
3D structure
PDB4u1n A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
ChainA
Resolution1.77 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 R62 N63 A69 Q70 T73 E76 S77 Y84 Y99 Y116 T143 W147 A150 D156 Y159 W167 Y171 Y8 R63 N64 A70 Q71 T74 E77 S78 Y85 Y100 Y117 T144 W148 A151 D157 Y160 W168 Y172
External links
PDB RCSB:4u1n, PDBe:4u1n, PDBj:4u1n
PDBsum4u1n
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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