Structure of PDB 4u1m Chain A

Receptor sequence
>4u1mA (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAP
WIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMYG
CDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGTCVEWLRRYLENGKDTLERADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEPS
3D structure
PDB4u1m A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
ChainA
Resolution1.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 R62 N63 Y67 A69 Q70 E76 S77 N80 Y84 Y99 Y116 Y123 T143 W147 A150 D156 Y159 W167 Y171 Y7 R62 N63 Y67 A69 Q70 E76 S77 N80 Y84 Y99 Y116 Y123 T143 W147 A150 D156 Y159 W167 Y171
External links
PDB RCSB:4u1m, PDBe:4u1m, PDBj:4u1m
PDBsum4u1m
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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