Structure of PDB 4u1k Chain A

Receptor sequence
>4u1kA (length=277) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHDQYAYDGKDYIALNEDLRSWTAADTAAQITQRKWEA
AREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB4u1k A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
ChainA
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 Y59 R62 N63 I66 A69 Q70 S77 Y84 Y99 Y116 T143 K146 W147 A150 E152 Q155 R156 Y159 W167 Y171 Y8 Y60 R63 N64 I67 A70 Q71 S78 Y85 Y100 Y117 T144 K147 W148 A151 E153 Q156 R157 Y160 W168 Y172
External links
PDB RCSB:4u1k, PDBe:4u1k, PDBj:4u1k
PDBsum4u1k
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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