Structure of PDB 4u1i Chain A

Receptor sequence
>4u1iA (length=278) Species: 9606 (Homo sapiens) [Search protein sequence]
MGSHSMRYFYTSVSRPGRGEPRFISVGYVDDTQFVRFDSDAASPREEPRA
PWIEQEGPEYWDRNTQIYKAQAQTDRESLRNLRGYYNQSEAGSHTLQSMY
GCDVGPDGRLLRGHNQYAYDGKDYIALNEDLRSWTAADTAAQISQRKLEA
ARVAEQDRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISDHEA
TLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWTAVVV
PSGEEQRYTCHVQHEGLPKPLTLRWEPS
3D structure
PDB4u1i A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
ChainA
Resolution1.92 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 R62 N63 I66 Y67 Q70 T73 S77 N80 Y84 Y99 S143 Y159 W167 Y171 Y8 R63 N64 I67 Y68 Q71 T74 S78 N81 Y85 Y100 S144 Y160 W168 Y172
External links
PDB RCSB:4u1i, PDBe:4u1i, PDBj:4u1i
PDBsum4u1i
PubMed25808313
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

[Back to BioLiP]