Structure of PDB 4u0v Chain A

Receptor sequence
>4u0vA (length=243) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
HMNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFGISRM
TVRQALSNLVNEGLLYRLKGRGTFVSKPKMEQALQGLTSFTEDMKSRGMT
PGSRLIDYQLIDSTEELAAILGCGHPSSIHKITRVRLANDIPMAIESSHI
PFELAGELNESHFQSSIYDHIERYNSIPISRAKQELEPSAATTEEANILG
IQKGAPVLLIKRTTYLQNGTAFEHAKSVYRGDRYTFVHYMDRL
3D structure
PDB4u0v Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR.
ChainA
Resolution2.051 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GLP A S88 F89 T90 R133 R135 E145 S165 I166 Y167 R211 E222 Y228 S89 F90 T91 R134 R136 E146 S166 I167 Y168 R212 E223 Y229
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4u0v, PDBe:4u0v, PDBj:4u0v
PDBsum4u0v
PubMed25564531
UniProtO34817|NAGR_BACSU HTH-type transcriptional repressor NagR (Gene Name=nagR)

[Back to BioLiP]