Structure of PDB 4u0f Chain A

Receptor sequence
>4u0fA (length=201) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence]
PIVQNQMVHQCISPRTLNAWVKVVEEKAFSPEVIPMFSALSCGATPQDLN
TMLNTVGGHQAAMQMLKETINEEAAEWDRLHPVHIAPGQMREPRGSDIAG
TTSTLQEQIGWMTHNPPIPVGEIYKRWIILGLNKIVRMYSPTSILDIRQG
PKEPFRDYVDRFYKTLRAETLLVQNANPDCKTILKALGPGATLEEMMTAC
Q
3D structure
PDB4u0f Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 3A8 A N53 L56 N57 K70 I73 N74 T107 N50 L53 N54 K67 I70 N71 T101 MOAD: Kd=1.2uM
PDBbind-CN: -logKd/Ki=5.92,Kd=1.2uM
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:4u0f, PDBe:4u0f, PDBj:4u0f
PDBsum4u0f
PubMed25356722
UniProtP12493|GAG_HV1N5 Gag polyprotein (Gene Name=gag)

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