Structure of PDB 4u07 Chain A

Receptor sequence
>4u07A (length=323) Species: 9606 (Homo sapiens) [Search protein sequence]
AALNQALEMKRQGKREKAQKLFMHALKMDPDFVDALTEFGIFSEEDKDII
QADYLYTRALTISPYHEKALVNRDRTLPLVEEIDQRYFSIIDSKVKKVMS
INSALRRVMEETYYHHIYHTVAIEGNTLTLSEIRHILETRYAVPGKSLEE
QNEVIGMHAAMKYINTTLVSRIGSVTISDVLEIHRRVLGYVDPVEAGRFR
TTQVLVGHHIPPHPQDVEKQMQEFVQWLNSEEAMNLHPVEFAALAHYKLV
YIHPFIDGNGRTSRLLMNLILMQAGYPPITIRKEQRSDYYHVLEAANEGD
VRPFIRFIAKCTETTLDTLLFAT
3D structure
PDB4u07 Crystal structure of the human, FIC-domain containing protein HYPE and implications for its functions.
ChainA
Resolution2.64 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.108: protein adenylyltransferase.
3.1.4.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A E234 V316 V360 D367 G368 N369 G370 R371 R374 Y399 Y400 N407 E124 V206 V250 D257 G258 N259 G260 R261 R264 Y289 Y290 N297
External links
PDB RCSB:4u07, PDBe:4u07, PDBj:4u07
PDBsum4u07
PubMed25435325
UniProtQ9BVA6|FICD_HUMAN Protein adenylyltransferase FICD (Gene Name=FICD)

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