Structure of PDB 4tzu Chain A

Receptor sequence
>4tzuA (length=90) Species: 10090 (Mus musculus) [Search protein sequence]
TSLCCKQCQETEITTKNEIFSLSETLTVYKASNLNLIGRPSTVHSWFPGY
AWTIAQCKICASHIGWKFTATKKDMSPQKFWGLTRSALLP
3D structure
PDB4tzu Structural Basis for Responsiveness to Thalidomide-Analog Drugs Defined by the Crystal Structure of the Human Cereblon:DDB1:Lenalidomide Complex
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C325 C328 C393 C396 C5 C8 C57 C60
BS02 Y70 A H380 W382 W388 W402 F404 H44 W46 W52 W66 F68
External links
PDB RCSB:4tzu, PDBe:4tzu, PDBj:4tzu
PDBsum4tzu
PubMed
UniProtQ8C7D2|CRBN_MOUSE Protein cereblon (Gene Name=Crbn)

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