Structure of PDB 4tz8 Chain A

Receptor sequence
>4tz8A (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB4tz8 Fragment-Based Screening of the Bromodomain of ATAD2.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 39U A V1008 V1013 I1074 V30 V35 I96 MOAD: Kd=500uM
PDBbind-CN: -logKd/Ki=3.30,Kd=500uM
BindingDB: Kd=500000nM
External links
PDB RCSB:4tz8, PDBe:4tz8, PDBj:4tz8
PDBsum4tz8
PubMed25314628
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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