Structure of PDB 4tz2 Chain A

Receptor sequence
>4tz2A (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB4tz2 Fragment-Based Screening of the Bromodomain of ATAD2.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 39R A V1008 F1009 Y1021 M1029 I1056 N1064 I1074 V30 F31 Y43 M51 I78 N86 I96 MOAD: Kd=350uM
PDBbind-CN: -logKd/Ki=3.46,Kd=350uM
External links
PDB RCSB:4tz2, PDBe:4tz2, PDBj:4tz2
PDBsum4tz2
PubMed25314628
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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