Structure of PDB 4tyl Chain A

Receptor sequence
>4tylA (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB4tyl Fragment-Based Screening of the Bromodomain of ATAD2.
ChainA
Resolution1.85 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 39O A V1008 V1013 Y1063 N1064 I1074 V30 V35 Y85 N86 I96 MOAD: Kd=600uM
PDBbind-CN: -logKd/Ki=3.22,Kd=600uM
BindingDB: Kd=600000nM
External links
PDB RCSB:4tyl, PDBe:4tyl, PDBj:4tyl
PDBsum4tyl
PubMed25314628
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

[Back to BioLiP]