Structure of PDB 4twz Chain A

Receptor sequence
>4twzA (length=327) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
KQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGG
LPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYAR
KLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEI
EGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGN
PETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPF
KQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANA
TAWLKDNPETAKEIEKKVRELLLSNPN
3D structure
PDB4twz Loop L1 governs the DNA-binding specificity and order for RecA-catalyzed reactions in homologous recombination and DNA repair
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E285 A287 W290 E280 A282 W285
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140297 DNA-binding transcription factor binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0000725 recombinational repair
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0010212 response to ionizing radiation
GO:0019985 translesion synthesis
GO:0035825 homologous recombination
GO:0048870 cell motility
Cellular Component
GO:0005737 cytoplasm
GO:0009355 DNA polymerase V complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4twz, PDBe:4twz, PDBj:4twz
PDBsum4twz
PubMed25561575
UniProtP0A7G6|RECA_ECOLI Protein RecA (Gene Name=recA)

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