Structure of PDB 4tuz Chain A

Receptor sequence
>4tuzA (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
3D structure
PDB4tuz A structural perspective on nuclear receptors as targets of environmental compounds.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I358 L372 D538 E542 I54 L68 D226 E230
BS02 36J A L346 L349 A350 E353 L387 L391 F404 M421 H524 L525 L42 L45 A46 E49 L83 L87 F100 M117 H212 L213
External links
PDB RCSB:4tuz, PDBe:4tuz, PDBj:4tuz
PDBsum4tuz
PubMed25500867
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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