Structure of PDB 4tu4 Chain A

Receptor sequence
>4tu4A (length=130) Species: 9606 (Homo sapiens) [Search protein sequence]
SMQEEDTFRELRIFLRNVTHRLAIDKRFRVFTKPVDPDEVPDYVTVIKQP
MDLSSVISKIDLHKYLTVKDYLRDIDLICSNALEYNPDRDPGDRLIRHRA
CALRDTAYAIIKEELDEDFEQLCEEIQESR
3D structure
PDB4tu4 Observed bromodomain flexibility reveals histone peptide- and small molecule ligand-compatible forms of ATAD2.
ChainA
Resolution1.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 37N A R1007 V1008 V1013 D1014 E1017 Y1063 N1064 I1074 R29 V30 V35 D36 E39 Y85 N86 I96 MOAD: Kd=175uM
PDBbind-CN: -logKd/Ki=3.76,Kd=175uM
External links
PDB RCSB:4tu4, PDBe:4tu4, PDBj:4tu4
PDBsum4tu4
PubMed25486442
UniProtQ6PL18|ATAD2_HUMAN ATPase family AAA domain-containing protein 2 (Gene Name=ATAD2)

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