Structure of PDB 4tpg Chain A

Receptor sequence
>4tpgA (length=459) Species: 211586 (Shewanella oneidensis MR-1) [Search protein sequence]
VSKTHSFMTVSLIELWERFGYYGMQALIVYFMVQRLGFDDSRANLVWSAC
AALIYVSPAIGGWVGDKILGTKRTMLLGAGILSVGYALMTVPTENTWFMF
SALGVIVVGNGLFKPNAGNLVRKIYESKIDSAFTIYYMAVNVGSTFSMLL
TPWIKDYVNAQYGNEFGWHAAFAVCCVGILVGLGNYALMHKSLANYGSEP
DTRPVNKKSLAIVLALAALSVVASAIILEYEDVARVFVYAAGVAVLGIFF
HLIRPSERAGLIAALILTVQTVFFFIFYQQMSTSLALFALRNVDWDFQVF
GTHLWTWSPAQFQALNPIWIMVLSPVLAWIAAKFALGFAVVAIGFFIYGF
AGQFAVNGKTSSWVMIWGYASYSLGELLVSGLGLAMIARYFMMGAYFVAS
GISQYLGGVVANFASVPQDLVDPLQTLPVYTNLFNKLGVAAVVCTIIALA
VLPLMRRLT
3D structure
PDB4tpg Selectivity mechanism of a bacterial homolog of the human drug-peptide transporters PepT1 and PepT2.
ChainA
Resolution3.91 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R25 Y28 Y29 K121 Y147 N151 R18 Y21 Y22 K114 Y137 N141
Gene Ontology
Molecular Function
GO:0015333 peptide:proton symporter activity
GO:0022857 transmembrane transporter activity
GO:0042802 identical protein binding
GO:0042937 tripeptide transmembrane transporter activity
GO:0071916 dipeptide transmembrane transporter activity
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015833 peptide transport
GO:0035442 dipeptide transmembrane transport
GO:0042939 tripeptide transport
GO:0055085 transmembrane transport
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:4tpg, PDBe:4tpg, PDBj:4tpg
PDBsum4tpg
PubMed25064511
UniProtQ8EHE6

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