Structure of PDB 4tm7 Chain A

Receptor sequence
>4tm7A (length=243) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence]
SDTVIERHADTAALVAAAGDRLVDAISSAIGERGQATIVLTGGGTGIGLL
KRVRERSGEIDWSKVHIYWGDERFVPQDDDERNDKQAREALLDHIGIPPV
NVHAMAASDGEFGDDLEAAAAGYAQLLSADFDSSVPGFDVHLLGMGGEGH
VNSLFPDTDAVRETERLVVGVSDSPKPPPRRITLTLPAVQNSREVWLVVS
GEAKADAVAAAVGGADPVDIPAAGAVGRERTVWLVDEAAAAKL
3D structure
PDB4tm7 Enzyme repurposing of a hydrolase as an emergent peroxidase upon metal binding.
ChainA
Resolution1.39 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.31: 6-phosphogluconolactonase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU1 A H67 H104 H66 H103
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0017057 6-phosphogluconolactonase activity
GO:0046872 metal ion binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006098 pentose-phosphate shunt

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Molecular Function
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Biological Process
External links
PDB RCSB:4tm7, PDBe:4tm7, PDBj:4tm7
PDBsum4tm7
PubMed29218172
UniProtA0QWX6

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