Structure of PDB 4tkn Chain A

Receptor sequence
>4tknA (length=256) Species: 9606 (Homo sapiens) [Search protein sequence]
PTEEVSLEVLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSL
FLVREKEDGAFSFVRKLQEFELPYVSVTSLRSQEYKIVLRKSYWDSAYDD
DVMENRVGLNLLYAQTVSDIERGWILVTKEQHRQLKSLQEKVSKKEFLRL
AQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQLRLREGSFRVTR
MRCWRVTSSVPVRLELAFEYLMSKDRLQWVTITSPQAIMMSICLQSMVDE
LMVKKS
3D structure
PDB4tkn Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1).
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A T316 R317 M318 R319 C320 W321 V380 L383 M384 T199 R200 M201 R202 C203 W204 V248 L251 M252
Gene Ontology
Molecular Function
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0006886 intracellular protein transport
GO:0007165 signal transduction
Cellular Component
GO:0005856 cytoskeleton

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4tkn, PDBe:4tkn, PDBj:4tkn
PDBsum4tkn
PubMed25059659
UniProtQ15036|SNX17_HUMAN Sorting nexin-17 (Gene Name=SNX17)

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