Structure of PDB 4s04 Chain A

Receptor sequence
>4s04A (length=219) Species: 1380908 (Klebsiella pneumoniae JM45) [Search protein sequence]
MKILVIEDDALLLQGLILAMQSEGYVCDGVSTAHEAALSLASNHYSLIVL
DLGLPDEDGLHFLSRMRREKMTQPVLILTARDTLEDRISGLDTGADDYLV
KPFALEELNARIRALLRRHNNQGDNEISVGNLRLNVTRRLVWLGETALDL
TPKEYALLSRLMMKAGSPVHREILYNDIYSGDNEPATNTLEVHIHNLREK
IGKSRIRTVRGFGYMLANN
3D structure
PDB4s04 Structure and dynamics of polymyxin-resistance-associated response regulator PmrA in complex with promoter DNA.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T151 K153 Y179 T187 N188 R210 T151 K153 Y179 T187 N188 R210 PDBbind-CN: Kd=200.6nM
BS02 dna A H195 R198 T208 R210 G211 Y214 H195 R198 T208 R210 G211 Y214 PDBbind-CN: Kd=200.6nM
BS03 BEF A D51 G53 T79 A80 K101 D51 G53 T79 A80 K101
BS04 MG A D8 D51 G53 D8 D51 G53
Gene Ontology
Molecular Function
GO:0000156 phosphorelay response regulator activity
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol
GO:0032993 protein-DNA complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4s04, PDBe:4s04, PDBj:4s04
PDBsum4s04
PubMed26564787
UniProtA0A0R4I965

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