Structure of PDB 4rwt Chain A

Receptor sequence
>4rwtA (length=369) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
ALVVDNGSGMCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGD
EAQSKRGILTLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPEEHPVLLT
EAPLNPKANREKMTQIMFETFNTPAMYVAIQAVLSLYASGRTTGIVLDSG
DGVSHTVPIYEGYALPHAILRLDLAGRDLTDYLMKILTERGYSFTTTAER
EIVRDIKEKLCYVALDFEQEMATAASSSSLEKSYELPDGQVITIGNERFR
CPEALFQPSFLGMEACGIHETTYNSIMKCDVDIREDLYANTVLSGGTTMY
PGIADRMQKEITALAKSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMW
ISKQEYDESGPSIVHRKCF
3D structure
PDB4rwt Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells.
ChainA
Resolution2.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A G13 S14 M16 K18 G156 D157 G182 K213 E214 G302 M305 Y306 K336 G7 S8 M10 K12 G150 D151 G176 K207 E208 G296 M299 Y300 K330
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0000281 mitotic cytokinesis
GO:0006338 chromatin remodeling
GO:0007291 sperm individualization
GO:0030723 ovarian fusome organization
GO:0032507 maintenance of protein location in cell
GO:0035148 tube formation
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0031011 Ino80 complex
GO:0035060 brahma complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4rwt, PDBe:4rwt, PDBj:4rwt
PDBsum4rwt
PubMed26417072
UniProtP10987|ACT1_DROME Actin-5C (Gene Name=Act5C)

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