Structure of PDB 4rvr Chain A

Receptor sequence
>4rvrA (length=117) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVI
KKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGH
NMRKYFEKKWTDTFKVS
3D structure
PDB4rvr Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
ChainA
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3WQ A W1887 P1888 P1892 V1893 V1898 I1950 W32 P33 P37 V38 V43 I95 PDBbind-CN: -logKd/Ki=6.87,Kd=136nM
BindingDB: Kd=60nM,IC50=430nM
External links
PDB RCSB:4rvr, PDBe:4rvr, PDBj:4rvr
PDBsum4rvr
PubMed25799074
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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