Structure of PDB 4rtw Chain A

Receptor sequence
>4rtwA (length=57) Species: 9031 (Gallus gallus) [Search protein sequence]
TFVALYDYVSRTETDLSFKKGERLQIVNNTEGDWWLAHSLTTGRTGYIPS
NYVAPSD
3D structure
PDB4rtw Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
ChainA
Resolution1.24 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y90 Y92 R95 T96 D99 E115 W118 P133 N135 Y136 Y6 Y8 R11 T12 D15 E31 W34 P49 N51 Y52
BS02 peptide A T126 G127 T42 G43
External links
PDB RCSB:4rtw, PDBe:4rtw, PDBj:4rtw
PDBsum4rtw
PubMed
UniProtP00523|SRC_CHICK Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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