Structure of PDB 4rsz Chain A

Receptor sequence
>4rszA (length=104) Species: 9796 (Equus caballus) [Search protein sequence]
GDVEKGKKIFVQKCAQCHTVEKGGKHKTGPNLHGLFGRKTGQAPGFTYTD
ANKNKGITWKEETLMEYLENPKKYIPGTKMIFAGIKKKTEREDLIAYLKK
ATNE
3D structure
PDB4rsz The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome c.
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HEC A K13 C14 C17 H18 G29 P30 Y48 T49 N52 W59 Y67 T78 K79 M80 I81 K13 C14 C17 H18 G29 P30 Y48 T49 N52 W59 Y67 T78 K79 M80 I81
BS02 CPT A E61 M65 E92 E61 M65 E92
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008289 lipid binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006123 mitochondrial electron transport, cytochrome c to oxygen
GO:0006915 apoptotic process
GO:0018063 cytochrome c-heme linkage
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001056 positive regulation of cysteine-type endopeptidase activity
Cellular Component
GO:0005739 mitochondrion
GO:0005758 mitochondrial intermembrane space
GO:0005829 cytosol
GO:0070069 cytochrome complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4rsz, PDBe:4rsz, PDBj:4rsz
PDBsum4rsz
PubMed25567806
UniProtP00004|CYC_HORSE Cytochrome c (Gene Name=CYCS)

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