Structure of PDB 4rrq Chain A

Receptor sequence
>4rrqA (length=141) Species: 272844 (Pyrococcus abyssi GE5) [Search protein sequence]
MRVLLIHSDYIEYEVKDKALKNPEPISEDMKRGRMEEVLVAFISVEKVDE
KNPEEVSLKAIEEISKVAEQVKAENVFVYPFAHLSSELAKPSVAMDILNR
VYQGLKERGFNVGKAPFGYYMAFKISCKGHPLAELSRTIVP
3D structure
PDB4rrq Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
ChainA
Resolution1.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.3: threonine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A3S A A19 V45 P80 F81 A82 A94 F117 G118 Y119 Y120 A19 V45 P80 F81 A82 A94 F117 G118 Y119 Y120 PDBbind-CN: -logKd/Ki=5.47,Kd=3.4uM
Gene Ontology
Molecular Function
GO:0004829 threonine-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4rrq, PDBe:4rrq, PDBj:4rrq
PDBsum4rrq
PubMed26113036
UniProtQ9UZ14|SYT_PYRAB Threonine--tRNA ligase (Gene Name=thrS)

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