Structure of PDB 4rqr Chain A

Receptor sequence
>4rqrA (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
GTAQEFVNCKIQPGKVVVFIKPTCPYCRRAQEILSQLPIKQGLLEFVDIT
ATNHTNEIQDYLQQLTGARTVPRVFIGKDCIGGCSDLVSLQQSGELLTRL
KQIGALQ
3D structure
PDB4rqr Cysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
ChainA
Resolution1.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COM A Y24 C82 S83 Y26 C84 S85
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0017080 sodium channel regulator activity
Biological Process
GO:0015949 nucleobase-containing small molecule interconversion
GO:0045838 positive regulation of membrane potential
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular exosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4rqr, PDBe:4rqr, PDBj:4rqr
PDBsum4rqr
PubMed25793542
UniProtP35754|GLRX1_HUMAN Glutaredoxin-1 (Gene Name=GLRX)

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