Structure of PDB 4rp8 Chain A

Receptor sequence
>4rp8A (length=442) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
VMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTS
TFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYSWVGYAVLLALAL
NICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTIICTAI
LVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKE
ESVEDLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVH
WTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAID
CAAIYSFAPNAVVWGFMWGTIGQLIAVGILVACGSSILIIPGFIPMFFSN
ATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVKLTGMSAWMGMADWS
ILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDA
3D structure
PDB4rp8 Crystal structure of a phosphorylation-coupled vitamin C transporter.
ChainA
Resolution2.359 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ASC A T86 Y87 H135 I136 Q139 H194 Q195 D314 F362 T72 Y73 H121 I122 Q125 H180 Q181 D300 F348 MOAD: Kd=6.1uM
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
GO:0090585 protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity
Biological Process
GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
GO:0015882 L-ascorbic acid transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:1902495 transmembrane transporter complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4rp8, PDBe:4rp8, PDBj:4rp8
PDBsum4rp8
PubMed25686089
UniProtP39301|ULAA_ECOLI Ascorbate-specific PTS system EIIC component (Gene Name=ulaA)

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