Structure of PDB 4rke Chain A

Receptor sequence
>4rkeA (length=176) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
GAMGMSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGAR
MITIDGKQIKLQIWDTAGLEAFRSITRSYYRGAAGALLVYDITRRETFNH
LTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEAFAREHGLVFM
ETSARTAANVEEAFINTAKEIYEKIQ
3D structure
PDB4rke Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP.
ChainA
Resolution2.0006 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A T15 G16 V17 G18 K19 S20 C21 F31 Q32 P33 V34 H35 T38 G64 N119 K120 D122 L123 S149 A150 R151 T19 G20 V21 G22 K23 S24 C25 F35 Q36 P37 V38 H39 T42 G68 N123 K124 D126 L127 S153 A154 R155
BS02 MG A S20 T38 S24 T42
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4rke, PDBe:4rke, PDBj:4rke
PDBsum4rke
PubMed25615965
UniProtO18333|RAB2_DROME Ras-related protein Rab-2 (Gene Name=Rab2)

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