Structure of PDB 4rje Chain A

Receptor sequence
>4rjeA (length=367) Species: 1377 (Aerococcus viridans) [Search protein sequence]
IEYNAPSEIKYIDVVNTYDLEEEASKVVPHGGFNYIAGASGDEWTKRAND
RAWKHKLLYPRLAQDVEAPDTSTEILGHKIKAPFIMAPIGAHGLAHATKE
AGTARAVSEFGTIMSISAYSGATFEEISEGLNGGPRWFQIYMAKDDQQNR
DILDEAKGDGATAIILTADSTVSGNRDRDVKNKFVYPFGMPIVQRYLTAE
GMSLNNIYGASKQKISPRDIEEIAAHSGLPVFVKGIQHPEDADMAIKAGA
SGIWVSNHGARQLYEAPGSFDTLPAIAERVNKRVPIVFDSGVRRGEHVAK
ALASGADVVALGRPVLFGLALGGWQGAYSVLDYFQKDLTRVMQLTGSQNV
EDLKGLDLFDNPYGYEY
3D structure
PDB4rje The Ala95-to-Gly substitution in Aerococcus viridans l-lactate oxidase revisited - structural consequences at the catalytic site and effect on reactivity with O2 and other electron acceptors.
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S122 Y146 T172 D174 K241 H265
Catalytic site (residue number reindexed from 1) S117 Y141 T167 D169 K234 H258
Enzyme Commision number 1.1.3.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FNR A P93 I94 G95 S122 Q144 Y146 T172 K241 H265 R268 D296 S297 G298 R300 G319 R320 P88 I89 G90 S117 Q139 Y141 T167 K234 H258 R261 D289 S290 G291 R293 G312 R313
BS02 PYR A Y40 Y146 R181 L211 Y215 H265 R268 Y35 Y141 R176 L204 Y208 H258 R261
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004459 L-lactate dehydrogenase activity
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4rje, PDBe:4rje, PDBj:4rje
PDBsum4rje
PubMed25423902
UniProtQ44467|LOX_AERVM L-lactate oxidase

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