Structure of PDB 4rg2 Chain A

Receptor sequence
>4rg2A (length=119) Species: 9606 (Homo sapiens) [Search protein sequence]
SFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILL
CDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRM
AVILSLEQGNRLREQYGLG
3D structure
PDB4rg2 Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3OO A F1519 D1521 M1584 F35 D37 M100 BindingDB: IC50=2.9e+4nM,Kd=2.2e+4nM
External links
PDB RCSB:4rg2, PDBe:4rg2, PDBj:4rg2
PDBsum4rg2
PubMed25590533
UniProtQ12888|TP53B_HUMAN TP53-binding protein 1 (Gene Name=TP53BP1)

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