Structure of PDB 4rg1 Chain A

Receptor sequence
>4rg1A (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
RGRPYTLSVALPGSILDNAQSPELRTYLAGQIARACAIFCVDEIVVFDEE
GQACVQLARILQYLECPQYLRKAFFPKHLQFAGLLNPLDSPHHMRQDEES
EFREGIVVDRPTRPGHGSFVNCGMKKEVKIDKNLEPGLRVTVRLNQQQDC
KTYHGKVVSSQDPRTKAGLYWGYTVRLASCLSAVFAEAPFQDGYDLTIGT
SERGSDVASAQLPNFRHALVVFGGLQGLEAGADADPNLEVAEPSVLFDLY
VNTCPGQGSRTIRTEEAILISLAALQPGLTQAGAR
3D structure
PDB4rg1 The Crystal Structure of Human C9orf114 in complex with S-adenosyl-homocysteine
ChainA
Resolution1.86 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A T289 S290 E291 R292 F311 G312 G313 L314 G316 N341 T342 I351 A356 T200 S201 E202 R203 F222 G223 G224 L225 G227 N252 T253 I262 A267
External links
PDB RCSB:4rg1, PDBe:4rg1, PDBj:4rg1
PDBsum4rg1
PubMed
UniProtQ5T280|CI114_HUMAN Putative methyltransferase C9orf114 (Gene Name=SPOUT1)

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