Structure of PDB 4rda Chain A

Receptor sequence
>4rdaA (length=203) Species: 9606 (Homo sapiens) [Search protein sequence]
DGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKN
LPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAA
LEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEK
AQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLG
PSE
3D structure
PDB4rda Interaction of the amyloid precursor protein-like protein 1 (APLP1) E2 domain with heparan sulfate involves two distinct binding modes.
ChainA
Resolution2.497 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SGN A H307 V380 H16 V89
BS02 IDS A H426 R429 H135 R138
BS03 SGN A R429 H430 H433 R138 H139 H142
BS04 UAP A F310 K314 R369 H433 F19 K23 R78 H142
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4rda, PDBe:4rda, PDBj:4rda
PDBsum4rda
PubMed25760599
UniProtP51693|APLP1_HUMAN Amyloid beta precursor like protein 1 (Gene Name=APLP1)

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