Structure of PDB 4rcj Chain A

Receptor sequence
>4rcjA (length=188) Species: 9606 (Homo sapiens) [Search protein sequence]
HPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCST
EHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGV
WSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLE
KAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKE
3D structure
PDB4rcj Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K395 S396 Y397 D401 W411 C412 N441 G442 W465 K469 W470 N504 S505 R506 D507 K31 S32 Y33 D37 W47 C48 N77 G78 W101 K105 W106 N140 S141 R142 D143 PDBbind-CN: Kd=22uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4rcj, PDBe:4rcj, PDBj:4rcj
PDBsum4rcj
PubMed26318451
UniProtQ9BYJ9|YTHD1_HUMAN YTH domain-containing family protein 1 (Gene Name=YTHDF1)

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