Structure of PDB 4r8n Chain A

Receptor sequence
>4r8nA (length=132) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
LHKEPATLIKAIDGDTIKLMYKGQPMTFRLLLVDTPETKHPVEKYGPEAS
AFTKKMIENAKKVEVEFDKGQRTDKYGRGLAYVYADGKMVNEALVRQGLA
KVAYVYKPNNTHEQHLRKSEAQAKKEKLNIWS
3D structure
PDB4r8n Cavities in proteins
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D21 R35 D40 T41 E43 R87
Catalytic site (residue number reindexed from 1) D15 R29 D34 T35 E37 R78
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 THP A R35 D83 K84 Y85 R87 L89 Y113 Y115 R29 D74 K75 Y76 R78 L80 Y104 Y106
BS02 CA A D21 D40 T41 D15 D34 T35
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4r8n, PDBe:4r8n, PDBj:4r8n
PDBsum4r8n
PubMed
UniProtP00644|NUC_STAAU Thermonuclease (Gene Name=nuc)

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