Structure of PDB 4r7x Chain A

Receptor sequence
>4r7xA (length=150) Species: 9606 (Homo sapiens) [Search protein sequence]
LGKVKSLTISFDCLNNVPVYSSGDTVSGRVNLEVTGEIRVKSLKIHARGH
AKVRWTESRNTAYTQNYTEEVEYFNHKDILIGHFHTIHSGRHEYAFSFEL
PQTPLATSFEGRHGSVRYWVKAELHRPWLLPVKLKKEFTVFEHIDINTPS
3D structure
PDB4r7x Insights into beta 2-adrenergic receptor binding from structures of the N-terminal lobe of ARRDC3.
ChainA
Resolution2.61 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 PO4 A H54 K56 R135 W137 K153 H50 K52 R117 W119 K135
BS02 PO4 A H50 K139 E141 K151 H46 K121 E123 K133
BS03 PO4 A K45 H143 K41 H125
BS04 PO4 A E80 N83 E72 N75
BS05 PO4 A H110 Y112 H92 Y94
External links
PDB RCSB:4r7x, PDBe:4r7x, PDBj:4r7x
PDBsum4r7x
PubMed25220262
UniProtQ96B67|ARRD3_HUMAN Arrestin domain-containing protein 3 (Gene Name=ARRDC3)

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