Structure of PDB 4r75 Chain A

Receptor sequence
>4r75A (length=318) Species: 715 (Actinobacillus pleuropneumoniae) [Search protein sequence]
KGRLVIYCSATNVMCENAAKTFEQKYDVKTSFIRNGSGSTFAKIEAEKNN
PQADVWYGGTLDPQSQAGELGLLEAYRSPNIDQIMPKFQDPAKVKGNLSS
AVYIGILGFAVNTERLKKLGIEKIPQCWNDLTDPKLKGEIQIADPQSSGT
AYTAIATFAQLWGEDKAFDYFKHLHPNISQYTKSGITPARNAARGETTVG
IGFLHDYALEKEQGAPLEMVVPCEGTGYELGGVSILKGARNLDNAKLFVD
FALSKEGQETAWKKGQALQTLTNTTAEQSPLAFDLTKLKLIDYDFEKYGA
SDERKRLINKWVDEIKLA
3D structure
PDB4r75 Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen.
ChainA
Resolution1.278 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 S7P A T11 G36 S37 G59 T60 Y103 S148 G149 T150 G185 H205 D206 E229 T11 G36 S37 G59 T60 Y103 S148 G149 T150 G185 H205 D206 E229 MOAD: Kd=57nM
PDBbind-CN: -logKd/Ki=7.24,Kd=57nM
Gene Ontology
Molecular Function
GO:0030975 thiamine binding
GO:0030976 thiamine pyrophosphate binding
Biological Process
GO:0015888 thiamine transport
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r75, PDBe:4r75, PDBj:4r75
PDBsum4r75
PubMed26295949
UniProtA3N294

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