Structure of PDB 4r6r Chain A

Receptor sequence

>4r6rA (length=133) Species: 3490 (Artocarpus integer) [Search protein sequence]

GKAFDDGAFTGIREINLSYNKETAIGDFQVVYDLNGSPYVGQNHKSFITG
FTPVKISLDFPSEYIMEVSGYTGNVSGYVVVRSLTFKTNKKTYGPYGVTS
GTPFNLPIENGLIVGFKGSIGYWLDYFSMYLSL

3D structure

PDB

4r6r Jacalin-carbohydrate interactions: distortion of the ligand molecule as a determinant of affinity.

Chain

Resolution

1.38 Å

3D
structure

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	T72 V79 F104 D125 Y126 F127 S128 M129 Y130 L131	T72 V79 F104 D125 Y126 F127 S128 M129 Y130 L131
BS02	peptide	A	N105 P107 E109 N110 L133	N105 P107 E109 N110 L133
BS03	peptide	A	T10 F60 P61 Y64 N110 G111 L112 L133	T10 F60 P61 Y64 N110 G111 L112 L133
BS04	147	A	G1 Y78 G121 Y122 W123 D125	G1 Y78 G121 Y122 W123 D125	MOAD: Ka=2370M^-1

Gene Ontology

	Molecular Function
GO:0019862	IgA binding
GO:0030246	carbohydrate binding

	Biological Process
GO:0008150	biological_process

	Cellular Component
GO:0005575	cellular_component

External links

PDB	RCSB:4r6r, PDBe:4r6r, PDBj:4r6r
PDBsum	4r6r
PubMed	25664742
UniProt	P18670\|LECA_ARTIN Agglutinin alpha chain