Structure of PDB 4r4q Chain A

Receptor sequence
>4r4qA (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
HMVGQLSRGAIAAIMQKGDTNIKPILQVINIRPITTGNSPPRYRLLMSDG
LNTLSSFMLATQLNPLVEEEQLSSNCVCQIHRFIVNTLKDGRRVVILMEL
EVLKSAEAVGVKIGNPVPYNE
3D structure
PDB4r4q Diphenylpyrazoles as replication protein a inhibitors.
ChainA
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 3HZ A I33 R41 R43 S55 M57 A59 T60 N85 L87 R91 V93 I95 I34 R42 R44 S56 M58 A60 T61 N86 L88 R92 V94 I96 PDBbind-CN: -logKd/Ki=5.09,Kd=8.2uM
Gene Ontology
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r4q, PDBe:4r4q, PDBj:4r4q
PDBsum4r4q
PubMed25699140
UniProtP27694|RFA1_HUMAN Replication protein A 70 kDa DNA-binding subunit (Gene Name=RPA1)

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