Structure of PDB 4r3i Chain A

Receptor sequence
>4r3iA (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
3D structure
PDB4r3i Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A K361 S362 N363 N367 W377 S378 L380 P381 V382 R404 E405 W428 M434 K472 I473 G474 R475 D476 K18 S19 N20 N24 W34 S35 L37 P38 V39 R61 E62 W85 M91 K129 I130 G131 R132 D133 PDBbind-CN: Kd=2uM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:4r3i, PDBe:4r3i, PDBj:4r3i
PDBsum4r3i
PubMed25242552
UniProtQ96MU7|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)

[Back to BioLiP]