Structure of PDB 4r2y Chain A

Receptor sequence
>4r2yA (length=64) Species: 9606 (Homo sapiens) [Search protein sequence]
ENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQVQ
QHCPMCRQEWKFKE
3D structure
PDB4r2y Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
ChainA
Resolution1.755 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C23 C26 H56 C59 C3 C6 H36 C39
BS02 ZN A C51 H53 C31 H33
BS03 ZN A C34 C37 C44 H58 C14 C17 C24 H38
BS04 ZN A C73 C76 C53 C56
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0097602 cullin family protein binding
Biological Process
GO:0031145 anaphase-promoting complex-dependent catabolic process
Cellular Component
GO:0005680 anaphase-promoting complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:4r2y, PDBe:4r2y, PDBj:4r2y
PDBsum4r2y
PubMed25306923
UniProtQ9NYG5|APC11_HUMAN Anaphase-promoting complex subunit 11 (Gene Name=ANAPC11)

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